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décapsidation du rein
Sep 5, 2020 14:43
3 yrs ago
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French term

Ac. polyclonal de lapin anti-Ag

French to English Medical Biology (-tech,-chem,micro-) UK English
Rabbit polyclonal anti-Ag antibody?
Proposed translations (English)
5 Anti-antigen, rabbit polyclonal antibody
3 -1 Rabbit antigen (Ag) polyclonal antibody

Discussion

José Patrício Sep 7, 2020:
OK
Michael Barnett Sep 7, 2020:
@Jose 2 Hi Jose. Ms. Finch has provided some additional details, but even when such details are not provided, I often can surmise the context from my familiarity with what is current in the medical literature.

In this case, the antibodies are produced by the rabbits and are harvested by the product manufacturer for use in a laboratory test. The rabbits are subjected to some antigen, and the rabbits manufacture antibodies against it. These antibodies are used in an ELISA test to detect if the antigen is present in the sample being tested.
José Patrício Sep 7, 2020:
Yes, but they are harmful antibodies which will be fought by the antibodies of the immunological system. See my last note, please.
Michael Barnett Sep 7, 2020:
@Jose Hi Jose. If I understand you correctly, you believe that the antigen is produced by the rabbit. I believe that you are incorrect. It is the rabbit which is producing the antibodies, not the antigen. Also, I do not understand what you are saying in the last part of your sentence. Could you rephrase that?
José Patrício Sep 7, 2020:
Michael, excuse me, I think the comma isn’t necessary because I suppose that the sense of the text (that we don’t see) is the antibody against the rabbit antigen which releases the harmful antibodies which will be fought by the immunological system.
Emmanuella Sep 5, 2020:
https://gentaur.com/search/rabbit polyclonal?page=1

Proposed translations

1 day 8 hrs
Selected

Anti-antigen, rabbit polyclonal antibody

I included the comma to avoid any confusion such as I mentioned about Jose's suggestion.
Note from asker:
Thanks Michael. I do miss the days when most people knew how to use commas in strings of adjectives.
See https://ca.vwr.com/store/catalog/product.jsp?product_id=26577572 which backs your answer, but uses "Ag" for "antigen" and no comma.
Something went wrong...
4 KudoZ points awarded for this answer.
-1
1 hr

Rabbit antigen (Ag) polyclonal antibody

ac=anticorps [Eng antigen]
anti-Ag=antigen (Ag) [Eng]
In immunology, an antigen (Ag) is a molecule or molecular structure, such as may be present at the outside of a pathogen, - https://en.wikipedia.org/wiki/Antigen
Custom mouse polyclonal antibody service packages including peptide synthesis - https://www.genscript.com/custom-mouse-polyclonal-antibody-s...
Mouse: Primarily used for generating monoclonal antibodies due to the small volume of antibody that can be obtained. - https://www.thermofisher.com/pt/en/home/life-science/antibod...
gclid=EAIaIQobChMI7Zy1w7DS6wIVzAJ7Ch1OmQAZEAAYASAAEgLrqvD_BwE&ef_id=EAIaIQobChMI7Zy1w7DS6wIVzAJ7Ch1OmQAZEAAYASAAEgLrqvD_BwE:G:s&s_kwcid=AL!3652!3!457007856179!e!!g!!polyclonal%20antibody%20service&cid=bid_pca_aup_r01_co_cp1359_pjt0000_bid00000_0se_gaw_nt_pur_con
Goat: The large-scale production option for polyclonal antibodies - the same link
Les anticorps polyclonaux correspondent à un mélange d'anticorps produits par clones de plasmocyles, les plasmocytes étant des lymphocytes B différenciés qui produisent des anticorps. - https://www.futura-sciences.com/sante/definitions/medecine-a...

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Note added at 1 dia 10 horas (2020-09-07 01:25:57 GMT)
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an·ti·gen (ăn′tĭ-jən) also an·ti·gene (-jēn′)
n.
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite. - https://www.thefreedictionary.com/antigene#:~:text=antigene-...

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Note added at 1 dia 11 horas (2020-09-07 01:48:29 GMT)
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Selon le sens de la phrase (que nous ne voyons pas) il s’agit de l’anticorps qui agira sur l’antigène du lapin.

Un antigène est une macromolécule naturelle ou synthétique qui, reconnue par des anticorps ou des cellules du système immunitaire d’un organisme, est capable de déclencher chez celui-ci une réponse immunitaire. - https://fr.wikipedia.org/wiki/Antigène
L’antigène est toute substance étrange à l’organisme qui déclenche des anticorps. Le système immunologique répond à l’antigène en produisant une substance appelée anticorps et celui-ci ira agir contre l’antigène.










Note from asker:
Thanks José. However, I am really looking for an answer from a specialist in the field, rather than dictionary definitions of antigen combined with word-crunching. As for context. The only context is that this would be used in ELISA and is mentioned in a training MCQ.
Peer comment(s):
disagree Michael Barnett : The main problem here is that the word order creates ambiguity. Is it rabbit antibody against an unspecified antigen or polyclonal antibodies against rabbit antigen? I believe the first meaning was the intended.
1 day 7 hrs
see my last note: an·ti·gen...
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