This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
  1. KudoZ™ Top
  2. English to French
  3. Biology (-tech,-chem,micro-)

recombinant antibody

French translation: Anticorps recombinant

For term searches and specialty glossaries, please try the new GBK glossaries
00:55 Sep 14, 2020
English to French translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical: Pharmaceuticals, Medical (general)
English term or phrase: recombinant antibody
Definition from Pharma IQ:
A Recombinant Antibody is defined as an antibody produced by genetic engineering. Recombinant antibody has significant advantages compared with the conventional antibody and there for its use becoming more popular now days. The fact that no animals are needed in the manufacturing procedure of the recombinant antibodies, in addition, the manufacturing time is relatively short compared with the conventional method. Moreover, the quality of the final product is higher that these of the non recombinant method.

Example sentence(s):
  • By the recombinant DNA technology, link purified genes of VH and VL with prokaryotic expression vector which requires select in advance based on your target recombinant antibody fragments. If you need scfv fragment antibody, linker must be designed in your PCR strategy. Creative Biolabs
  • One of the first recombinant antibody fusions with therapeutic potential consisted of a monoclonal antibody, specific for the fibrin β-chain, in which the Fc portion was replaced with an engineered version of the β-chain of tissue-type plasminogen activator (t-PA) (144). Science Direct
  • Also delivering custom recombinant antibody production, GenScript has invested many years in optimizing its cell lines, gene synthesis and plasmid preparation, transfection reagents, and media systems to offer a suite of different services. Biocompare
Glossary-building KudoZ




Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


This question is closed

French translation:Anticorps recombinant
Definition:
Aucun animal de laboratoire n'est utilisé pour la production d'anticorps recombinants. Ces anticorps sont uniquement produits in vitro. Pour ce faire, des micro-organismes sont génétiquement transformés, par exemple en introduisant une séquence ADN encodant l'anticorps dans le génome de la cellule hôte.
Selected response from:

Veronica Montserrat
France
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
4 +3Anticorps recombinant
Veronica Montserrat


  

Translations offered


5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
Anticorps recombinant


Definition from anticorps-enligne.fr:
Aucun animal de laboratoire n'est utilisé pour la production d'anticorps recombinants. Ces anticorps sont uniquement produits in vitro. Pour ce faire, des micro-organismes sont génétiquement transformés, par exemple en introduisant une séquence ADN encodant l'anticorps dans le génome de la cellule hôte.

Example sentence(s):
  • La technique d’expression transitoire de gènes en cellules CHO (Chinese Hamster Ovary) est une méthode massivement utilisée pour produire rapidement et efficacement des candidats anticorps recombinants aux phases de découverte (‘‘Discovery’’) et d’optimisation des candidats et leur caractérisation (‘‘Lead Optimization & Characterization’’). - Biotem  
  • L'objectif de ces travaux est l'obtention et l'ingénierie d'anticorps neutralisant les toxines du risque biologique provoqué et la localisation de l'épitope de tels anticorps. En effet, les anticorps recombinants correspondent à la forme la plus moderne de la sérothérapie et ils sont une classe de molécules thérapeutiques actuellement en pleine expansion. Aujourd'hui 27 anticorps recombinants disposent d'une autorisation de mise sur le marché et plus de 200 sont en cours de développement. Bien que la production des anticorps recombinants soit délicate et couteuse, ils présentent une bonne tolérance comparée aux petites molécules synthétiques dont 90% échouent lors des essais cliniques, principalement à cause de problèmes de tolérance ou de pharmacocinétique. Les anticorps recombinants sont donc particulièrement bien adaptés au traitement des maladies causées par les agents du risque biologique puisqu'il n'est nécessaire de ne produire que des quantités relativement limités - Isolement de fragments d’anticorps rec  
Veronica Montserrat
France
Local time: 08:02
Native speaker of: Native in FrenchFrench
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Chrislène Murat
12 mins
Yes  Lionel-N
2 hrs
Yes  Christine HOUDY: https://www.anticorps-enligne.fr/resources/16/1211/anticorps...
1 day 12 hrs
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Return to KudoZ list

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.

See also:
ProZ.com term search
Search millions of term translations
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search