cytokine storm

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19:57 Jan 4, 2021
English to Japanese translations [PRO]
COVID-19 - Medical - Medical (general)
Additional field(s): Medical: Health Care, Medical (general), Journalism
English term or phrase: cytokine storm
Definition from Oxford English Dictionary:
an overactive immune response occurring in various infectious and non-infectious diseases, characterized by the excessive production of cytokines and resulting in intense localized or generalized inflammation.

Example sentence(s):
  • Researchers aren’t sure what percentage of severely ill patients will die from a cytokine storm, or even why some people who are infected will go on to have this reaction, while others won’t WebMD
  • Like many other viruses, particularly SARS, MERS, and influenza, the cytokine storm has been used as a warning sign for clinicians to recognize disease escalation. News Medical
  • The combination of hyperinflammation, coagulopathy, and low platelet counts places patients with cytokine storm at high risk for spontaneous hemorrhage. The New England Journal of Medicine
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
5 +1サイトカインストーム
Yasumichi Hayakawa


  

Translations offered


7 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
サイトカインストーム


Definition from 実験医学online:
サイトカインストーム
感染症や薬剤投与などの原因により,血中サイトカイン(IL-1,IL-6,TNF-αなど)の異常上昇が起こり,その作用が全身に及ぶ結果,好中球の活性化,血液凝固機構活性化,血管拡張などを介して,ショック・播種性血管内凝固症候群(DIC)・多臓器不全にまで進行する.この状態をサイトカインストーム(cytokine storm)という.

実験医学増刊 Vol.31 No.12

Example sentence(s):
  • 血中に炎症性サイトカイン等が放出され、悪寒、悪心、倦怠感、頭痛、発熱、頻脈、血圧変動等の種々の症状が起こる[2]。重症の病態をサイトカインストームと呼ぶ(下記参照)。抗胸腺細胞グロブリン(ウサギ由来-商品名:サイモグロブリン、ウマ由来-商品名:リンフォグロブリン(販売中止))、ムロモナブ-CD3(英語版)(マウス由来-商品名:オルソクローンOKT3[3](販売中止))、TGN1412(開発中止)等のほか、抗CD-20抗体(抗B細胞抗体)であるリツキシマブでも見られる。 - Wikipedia  
Yasumichi Hayakawa
Japan
Local time: 07:32
Native speaker of: Native in JapaneseJapanese
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Sunjin Gu
66 days
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