22:21 Aug 13, 2020 |
English to Spanish translations [PRO] Science - Chemistry; Chem Sci/Eng / CRISPRi-CasX proteins | |||||||
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| Selected response from: Kepa S S O (X) Colombia Local time: 16:56 | ||||||
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Summary of answers provided | ||||
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4 | enriquecimiento en veces |
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3 | nivel de enriquecimiento |
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nivel de enriquecimiento Explanation: Fold enrichment To measure the magnitude of enrichment. For example, 10% of user's genes are kinases versus 1% of genes in human genome (this is population background) are kinases. Thus, the fold enrichment is tenfold. Fold enrichment along with EASE score could rank the enriched terms in a more comprehensive way https://go.gale.com/ps/i.do?p=AONE&u=googlescholar&id=GALE|A... En cuanto, al nivel de enriquecimiento (Fold enrichment) de acuerdo con las recomendaciones Huang et al [87], este se tomó como interesante cuando supero el 1.5. http://bdigital.unal.edu.co/53978/1/carolinaarenasvalencia.2... |
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enriquecimiento en veces Explanation: Para estudiar los complejos que forman las proteínas con ADN se usa esta técnica que pudiera estar referida en el doc que traduces: ChIP-sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins. ChIP is a powerful method to selectively enrich for DNA sequences bound by a particular protein in living cells. https://en.m.wikipedia.org/wiki/ChIP_sequencing Fold Enrichment Method This normalization method is also called 'signal over background' or 'relative to the no-antibody control'. With this method, the ChIP signals are divided by the no-antibody signals, representing the ChIP signal as the fold increase in signal relative to the background signal. https://www.thermofisher.com › home ChIP Analysis | Thermo Fisher Scientific - US Ejemplo en español: "...sitios de unión a STAT en el locus Mcl1 . ... STAT5 ChIP se realizó sobre lisados de células NK fijados con formaldehído. Los datos representan el enriquecimiento en veces del promotor Mcl1 o las secuencias de ADN 3'-UTR en lisados de células NK tratadas con IL-15. El enriquecimiento de Cish se utiliza como control positivo." En este método el enriquecimiento de las regiones de ADN que interactúan con la proteína en estudio se expresa en "veces" con respecto a la muestra negativa o sin anticuerpo (fondo). Espero también te ayude. Saludos! -------------------------------------------------- Note added at 21 hrs (2020-08-14 19:27:25 GMT) -------------------------------------------------- "En veces" puede ir entre comas, como en la expresión "aumento, en veces,..." https://en.m.wikipedia.org/wiki/ChIP_sequencing |
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