メラニンの摘落(てきらく)

14:15 Aug 12, 2018
Japanese to English translations [PRO]
Medical - Medical (general) / Dermatology Term
Japanese term or phrase: メラニンの摘落(てきらく)
よろしくお願いいたします。

・・・昔、激しく日に焼けていた、という方の肩や背中にシミともほくろとも区別のつかないような斑点状の色素沈着がよくみられますが、これは、メラニンの摘落(てきらく)というものです。
Michael Mathieu (X)


Summary of answers provided
4 -1melanin pigmentation
Kayoko Kimura
2dropping off of melanine
cinefil
Summary of reference entries provided
定訳は無く様々な表現が使われている?
multiverse

Discussion entries: 4





  

Answers


8 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): -1
melanin pigmentation


Explanation:
摘落 is a typo of 滴落, I believe. Please see the website below. You can see abstract both in English and in Japanese


    https://www.jstage.jst.go.jp/article/nishinihonhifu/80/2/80_108/_article/-char/en
Kayoko Kimura
United States
Local time: 08:39
Specializes in field
Native speaker of: Native in JapaneseJapanese
PRO pts in category: 85
Notes to answerer
Asker: ご意見ありがとうございます。「様々な表現が使われている」と言いましたが、例えばどんな表現でしょうか??


Peer comments on this answer (and responses from the answerer)
disagree  multiverse: "melanin pigmentation"または"melanin hyper-pigmentation"は「滴落」そのものではなく「滴落」の結果を表す用語。
1 day 18 hrs
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8 hrs   confidence: Answerer confidence 2/5Answerer confidence 2/5
dropping off of melanine


Explanation:
https://ci.nii.ac.jp/naid/130004473911/
https://www.derm-hokudai.jp/textbook/pdf/2-03.pdf

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Note added at 8時間 (2018-08-12 22:24:38 GMT)
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原文を書いた人は、色素沈着のメカニズムを十分には理解していないように思われます。

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Note added at 8時間 (2018-08-12 22:28:46 GMT)
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drop outの例
https://www.sciencedirect.com/topics/neuroscience/pigmentati...
https://books.google.co.jp/books?id=QnfODgAAQBAJ&pg=PA383&lp...

cinefil
Japan
Local time: 22:39
Works in field
Native speaker of: Native in JapaneseJapanese
PRO pts in category: 254
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Reference comments


1 day 18 hrs
Reference: 定訳は無く様々な表現が使われている?

Reference information:
Pigmentary incontinence is a phenomenon observed in some inflammatory skin disorders. Clinically it may be seen as a slate-colored pigmentation. Histologically it is seen as an accumulation of melanin in the upper dermis. The possible mechanism for development of pigmentary incontinence is discussed based on a review of the literature and electron microscopic studies of fixed drug eruption.
https://www.sciencedirect.com/science/article/pii/S019096228...

Dermal hypermelanosis can be due to the production of melanin by ectopic dermal melanocytes (dermal melanocytosis), or to an abnormal transfer of melanin from epidermal cells to the dermis (pigmentary incontinence).
https://www.google.co.jp/search?biw=678&bih=356&ei=zG9yW_YZg...

leakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence.
www.em-consulte.com/en/article/775853

Dermal melanosis occurs when inflammation disrupts the basal cell layer, releasing melanin pigment, which is subsequently trapped by papillary dermal macrophages; this effect is also known as pigmentary incontinence.
https://www.consultant360.com/content/skin-disorders-older-a...

Histologically, pigmentary incontinence is caused by melanosome translocation from the epidermis to the dermis, usually following dermo-epidermal junction damage.
https://www.cosmetic-medicine.jp/list/strategy.htm
L
eakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence.
https://www.ncbi.nlm.nih.gov/pubmed/23522626

The dead keratinocytes spill their melanin into adjacent dermis in a processcalled pigmentary incontinence, where it is phagocytized by macrophages (melanophages).
https://books.google.co.jp/books?isbn=0323357970


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Note added at 2日 5時間 (2018-08-14 20:01:43 GMT)
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例文を見るには、「定訳は無く様々な表現が使われている?」をクリックしてくださいませ。

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Note added at 2日 16時間 (2018-08-15 07:05:44 GMT)
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Increased dermal pigmentation probably results from a dischargement of the melanin granules into the dermis secondary to melanocyte alterations.
https://www.ncbi.nlm.nih.gov/pubmed/464658

multiverse
Japan
Specializes in field
Native speaker of: Native in JapaneseJapanese
PRO pts in category: 8
Login to enter a peer comment (or grade)



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