barreiras hematoencefálica e hematoliquórica

English translation: blood–brain and blood–cerebrospinal fluid barrier

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Portuguese term or phrase:barreiras hematoencefálica e hematoliquórica
English translation:blood–brain and blood–cerebrospinal fluid barrier
Entered by: Eduardo López

03:37 Apr 2, 2020
Portuguese to English translations [PRO]
Medical - Medical: Health Care / Diabetes
Portuguese term or phrase: barreiras hematoencefálica e hematoliquórica
8. Alterações do diabetes mellitus no sistema nervoso central: avaliação de parâmetros astrocitários, comportamentais, da funcionalidade das barreiras hematoencefálica e hematoliquórica e o papel da exendina-4 na neuroproteção.


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Eduardo López
Puerto Rico
Local time: 09:45
blood–brain and blood–cerebrospinal fluid barrier
Explanation:
:)
Selected response from:

Filippe Vasconcellos de Freitas Guimarães
Brazil
Local time: 10:45
Grading comment
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Summary of answers provided
5 +1blood–brain and blood–cerebrospinal fluid barrier
Filippe Vasconcellos de Freitas Guimarães
3blood-brain and blood-CSF barriers (BBB & BCSFB)
Francisco Chagas


  

Answers


2 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
blood–brain and blood–cerebrospinal fluid barrier


Explanation:
:)


    https://www.ncbi.nlm.nih.gov/pubmed/19779720
Filippe Vasconcellos de Freitas Guimarães
Brazil
Local time: 10:45
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in PortuguesePortuguese
PRO pts in category: 120
Grading comment
Thank you!

Peer comments on this answer (and responses from the answerer)
agree  liz askew
3 hrs
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2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
blood-brain and blood-CSF barriers (BBB & BCSFB)


Explanation:
It would be unwise to provide a thorough explanation in regards to a topic that is very much out of my current "comfort-zone" so I shall let the references speak for themselves:

a) "The central nervous system (CNS) is tightly sealed from the changeable milieu of blood by the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier (BCSFB). While the BBB is considered to be localized at the level of the endothelial cells within CNS microvessels, the BCSFB is established by choroid plexus epithelial cells."
[Ref #2]


b) "O sistema nervoso central (SNC) é uma zona privilegiada, que normalmente é
protegido por três elementos estruturais: a BHE com a interface entre o encéfalo e
os vasos sanguíneos; a barreira sangue - liquido cefalorraquidiano (BSLCR), formada pelo plexo coróide e a membrana aracnóide com os vasos sanguíneos e o líquido
cefalorraquidiano;"
[http://www.scielo.br/pdf/rbti/v23n2/a16v23n2.pdf]

c) "Barreira hematoencefálica (BHE) é uma estrutura de permeabilidade altamente seletiva que protege o Sistema Nervoso Central (SNC) de substâncias potencialmente neurotóxicas presentes no sangue e sendo essencial para função metabólica normal do cérebro. É composta de células endoteliais estreitamente unidas, astrócitos, pericitos e diversas proteínas.
Barreira hematoliquórica: entre o sangue e o liquor. Há junções de oclusão no epitélio do plexo corioideo, que impede a passagem do liquor produzido para o sangue."
[https://www.passeidireto.com/arquivo/20576678/estudo-dirigid...]

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Note added at 2 hrs (2020-04-02 06:28:39 GMT)
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    Reference: http://www.scielo.br/pdf/anp/v35n3/01.pdf
    https://www.ncbi.nlm.nih.gov/pubmed/19779720
Francisco Chagas
United Kingdom
Local time: 13:45
Native speaker of: Native in PortuguesePortuguese
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