glucogenización del citoplasma

English translation: glycogenation of cytoplasm

20:34 Apr 28, 2021
Spanish to English translations [PRO]
Medical - Medical (general) / biopsy of cervical cone
Spanish term or phrase: glucogenización del citoplasma
This is the report of a biopsy of cervical cone. It comes from Mexico.

Se observa epitelio plano estratificado no queratinizado acantósico a expensas de **glucogenización del citoplasma**

Not much more context after that. Goes on to describe pérdida de maduración, la capa basal muestra hiperplasia, se identifican disqueratinocitos, etc. I don't see anything else relevant to that phrase.
wendy griswold
Local time: 22:34
English translation:glycogenation of cytoplasm
Explanation:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994530/
glycogenated squamous epithelium

ABSTRACT: The purpose of the present study was to assess the findings in cervical smears associated with intramuscular depot medroxyprogesterone acetate (Depo-Provera) contraception. Seventy-four cervical smears of reproductive-age patients on Depo-Provera were reviewed for cytologic abnormalities, predominant cell type, and intermediate cell glycogenation (extensive (EGly) = navicular cells / glycogenation in 10 or more high-powered fields (hpf); moderate (MGly) = 5-10 hpf; and focal (FGly) = less than 5 hpf). A control group of 38 nonpregnant patients without hormonal therapy was reviewed. Study group patients' (SGP) age ranged from 16-44 years (average 28.1); control group patients (CGP) from 17-42 years (average 29.4). Time since last menstrual period (LMP) for the SGP was 16.9 months (range 1-96); LMP for CGP was 18.2 days (range 5-33). Four (5.4%) SGP had squamous intraepithelial lesions (SIL), four (5.4%) atypical squamous cells of undetermined significance (ASCUS), and one (1.4%) atypical repair. No CGP had SIL or ASCUS. Seventy-three (98.6%) SGP had intermediate cell (IC) predominance; one had parabasal cell predominance. Of the CGP, 28 (73.7%) had IC predominance, nine (23.7%) superficial cell (SC) predominance and one (2.6%) had near equal IC and SC. EGly was seen in 22 (29.7%) SGP; two (5.3%) in CGP (chi-square 7.53; 0.95 = 3.84). MGly was seen in 29 (39.2%) SGP; 10 (26.3%) in CG. FGly was seen in 17 (22.9%) SGP; 14 (36.8%) in CGP. No glycogenation was seen in six (8.1%) SGP; 12 (31.6%) in CGP. Time since LMP was inversely proportional to glycogenation in SGP: EGly-LMP 11.6 months; MGly-LMP 14.9 months; FGly-LMP 15.0 months; and no glycogenation-LMP 22.5 months. Glycogenation of IC appears inversely proportional to Depo-Provera effect. EGly due to recent Depo-Provera administration mimics changes associated with pregnancy.
https://pubmed.ncbi.nlm.nih.gov/10945902/

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Note added at 27 mins (2021-04-28 21:02:13 GMT)
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Un detalle común en el epitelio vaginal es la glucogenización de los queratinocitos. Note que los citoplasmas de los estratos más superficiales tiene un aspecto vacío. http://www.facmed.unam.mx/deptos/biocetis/PDF/Portal de Recu...
Selected response from:

Cristina Zavala
Ecuador
Local time: 21:34
Grading comment
Many thanks
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1glycogenation of cytoplasm
Cristina Zavala
4glycogenization of cytoplasm
Marcelo Viera
Summary of reference entries provided
see
liz askew

Discussion entries: 3





  

Answers


26 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
glycogenation of cytoplasm


Explanation:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994530/
glycogenated squamous epithelium

ABSTRACT: The purpose of the present study was to assess the findings in cervical smears associated with intramuscular depot medroxyprogesterone acetate (Depo-Provera) contraception. Seventy-four cervical smears of reproductive-age patients on Depo-Provera were reviewed for cytologic abnormalities, predominant cell type, and intermediate cell glycogenation (extensive (EGly) = navicular cells / glycogenation in 10 or more high-powered fields (hpf); moderate (MGly) = 5-10 hpf; and focal (FGly) = less than 5 hpf). A control group of 38 nonpregnant patients without hormonal therapy was reviewed. Study group patients' (SGP) age ranged from 16-44 years (average 28.1); control group patients (CGP) from 17-42 years (average 29.4). Time since last menstrual period (LMP) for the SGP was 16.9 months (range 1-96); LMP for CGP was 18.2 days (range 5-33). Four (5.4%) SGP had squamous intraepithelial lesions (SIL), four (5.4%) atypical squamous cells of undetermined significance (ASCUS), and one (1.4%) atypical repair. No CGP had SIL or ASCUS. Seventy-three (98.6%) SGP had intermediate cell (IC) predominance; one had parabasal cell predominance. Of the CGP, 28 (73.7%) had IC predominance, nine (23.7%) superficial cell (SC) predominance and one (2.6%) had near equal IC and SC. EGly was seen in 22 (29.7%) SGP; two (5.3%) in CGP (chi-square 7.53; 0.95 = 3.84). MGly was seen in 29 (39.2%) SGP; 10 (26.3%) in CG. FGly was seen in 17 (22.9%) SGP; 14 (36.8%) in CGP. No glycogenation was seen in six (8.1%) SGP; 12 (31.6%) in CGP. Time since LMP was inversely proportional to glycogenation in SGP: EGly-LMP 11.6 months; MGly-LMP 14.9 months; FGly-LMP 15.0 months; and no glycogenation-LMP 22.5 months. Glycogenation of IC appears inversely proportional to Depo-Provera effect. EGly due to recent Depo-Provera administration mimics changes associated with pregnancy.
https://pubmed.ncbi.nlm.nih.gov/10945902/

--------------------------------------------------
Note added at 27 mins (2021-04-28 21:02:13 GMT)
--------------------------------------------------


Un detalle común en el epitelio vaginal es la glucogenización de los queratinocitos. Note que los citoplasmas de los estratos más superficiales tiene un aspecto vacío. http://www.facmed.unam.mx/deptos/biocetis/PDF/Portal de Recu...


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994530/
    https://pubmed.ncbi.nlm.nih.gov/10945902/
Cristina Zavala
Ecuador
Local time: 21:34
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 12
Grading comment
Many thanks

Peer comments on this answer (and responses from the answerer)
agree  liz askew: Liver Transplantation: Challenging Controversies and Topicshttps://books.google.co.uk › books Gregory T. Everson, ‎James F. Trotter · 2009 · ‎Medical ... in the absence of excessive alcohol ingestion (7). The histological characteristics of NASH are macr
14 hrs
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5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
glycogenization of cytoplasm


Explanation:
Abstract

Context.—The correct diagnosis and reporting of cervical in situ and invasive carcinoma are essential for the appropriate clinical management of patients with human papillomavirus–associated disease....

A, Benign squamous mucosa with glycogenization of cytoplasm forming pseudokoilocytes. The process involves the entire epithelium (hematoxylin-eosin, original magnification ×40). B, Low-grade squamous intraepithelial lesion (cervical intraepithelial neoplasia 1) with true cytologic atypia, koilocytosis, and parabasal proliferation   (hematoxylin-eosin, original magnification ×400).Figure 2.Adenocarcinoma in situ. The cells are pseudostratified and hyperchromatic with some cytoplasmic mucin 
https://meridian.allenpress.com/aplm/article/133/5/729/46075...

Marcelo Viera
Uruguay
Local time: 23:34
Specializes in field
Native speaker of: Spanish
PRO pts in category: 4
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Reference comments


14 hrs
Reference: see

Reference information:
Examples of FRCPath Part 1 style multiple choice questions ...https://www.virtualpathology.leeds.ac.uk › pdfs
PDF
The typical biopsy findings in alcoholic liver disease are a macrovesicular steatosis (with ... Diffuse nuclear glycogenation is a not-uncommon finding that may reflect underlying diabetes ... epithelial cells arranged in cords and trabeculae.

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 4558
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