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English to Turkish - Standard rate: 0.06 EUR per word / 30 EUR per hour
Source text - English The increase in mortality is attributed to excess GH and IGF-I. Because IGF-I is a general growth factor, somatic hypertrophy occurs across all organ systems, including but not limited to, acromegalic heart, increased muscle and soft tissue mass, and increased kidney size. Articular overgrowth of synovial tissue and hypertrophic arthropathy occur. Joint symptoms, back pain, and kyphosis are common presenting features. Other symptoms of soft tissue overgrowth include thick skin, hyperhidrosis (often malodorous), carpal tunnel syndrome, and other entrapment syndromes. Macroglossia may result in sleep apnea.
Translation - Turkish Mortalitedeki artış, aşırı GH ve IGF-1 seviyesine bağlıdır. IGF-1 genel bir büyüme faktörü olduğundan tüm organ sistemlerinde somatik büyümeye neden olmaktadır. Büyüyen organların başında kalp ve böbrek gelmektedir. Akromegalik kalpte kas ve yumuşak doku artışı olurken, böbrekte de büyüme meydana gelmektedir. Artiküler sinovyal dokudaki büyüme sonucu da hipertrofik artropati oluşmaktadır. Bunun sonucunda sıklıkla eklem şikâyetleri, sırt ağrısı, kifoz gibi semptomlar ortaya çıkmaktadır. Yumuşak doku büyümesine bağlı diğer semptomlar arasında cilt kalınlaşması, hiperhidrozis (genellikle kötü kokulu), karpal tünel sendromu ve diğer sıkışma sendromları sayılabilir. Makroglossinin uyku apnesine sebep olabildiği ayrıca belirtilmelidir.
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