Glossary entry

inglés term or phrase:

the patterns of gene expression across time points

español translation:

El patrón de expresión genética obtenido a través de tiempos puntuales

Aug 22, 2008 15:36
15 yrs ago
inglés term

the patterns of gene expression across time points

Non-PRO inglés al español Ciencias Biología (biotecnología/química, microbiología) molecular biology
how to translate time points into spanish
Votes to reclassify question as PRO/non-PRO:

PRO (1): Ana L Fazio-Kroll

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Discussion

Teresa Mozo Aug 22, 2008:
sería muy útil saber de qué tipo de documento se trata. Si es un texto científico u otra cosa, y el contexto o la frase en la que se emplea la expresión. A través el tiempo me suena muy literario.

Proposed translations

-1
2 días 19 minutos
Selected

El patrón de expresión genética obtenido a través de tiempos puntuales

Esta es la manera como yo lo interpreto, dada la frase:

"time points" se puede traducir como "tiempos puntuales". Son momentos específicos en el tiempo en donde se toma una muestra....es un momento ó punto exacto en el tiempo. No confundir con intervalos de tiempo. Intervalo de tiempo es, y valga la redundancia, el tiempo que transcurre entre un tiempo puntual en que fue recogida una muestra y otro tiempo puntual.

Para darte una idea, esos "time points" los podemos llamar "tiempos específicos de recolección de la muestra" ó "puntos específicos entre intervalos de tiempo".

Un ejemplo:
To address the question whether DosR-regulated genes are induced all at once or in a temporal cascade, we exposed M. tuberculosis to a sudden drop of oxygen from a high level of 10% dissolved oxygen tension (DOT) to a low level of 0.2% DOT and extracted samples from chemostat culture to obtain gene expression values from DNA microarrays.

"Samples were taken at nine time points over a period of 25 minutes" and the corresponding DOT recorded. ...

Replicates at time points are often not available in sufficient numbers due to the difficulties in obtaining biological samples. Fortunately, in the case of time course data, regression based methods can borrow information for error estimation across time points [6,7].
Here we outline an analysis strategy based on fitting regression splines with step basis functions to time course data. This method allows us to detect at which time point and hence under which oxygen tension each DosR-mediated gene was induced, providing new insights into the genetic program of DosR mediated gene regulation.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=22...

Otra explicación:
"A time point is a point in real, historical time. It is independent of the observer and the context. A time point is not a measurement of time, nor is it a specification of time. It is the point in time. The timepoints at which events occur can be known with various degrees of precision and approximation, but conceptually time points are point-like and not interval-like."

Espero te sea de ayuda.
Saludos!




Peer comment(s):

disagree M. C. Filgueira : "A través de tiempos puntuales" me suena muy mal. ¿Qué es un tiempo puntual? Yo diría "punto temporal", "momento" o, tal vez, simplemente, "intervalo de tiempo". En todo caso, con más contexto (párrafo completo) sería más fácil encontrar la mejor trad.
7 días
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4 KudoZ points awarded for this answer. Comment: "Gracias mil! Esta respuesta me parece mas precisa."
+1
7 minutos

los patrones de expresión genética a través del tiempo

option
Peer comment(s):

agree Carmen Valentin-Rodriguez
1 minuto
gracias
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1 hora

... la cronología o ...a través del tiempo

no creo que sea necesario apegarse literalmente...
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