Jul 9, 2015 10:34
8 yrs ago
2 viewers *
French term

cirrhose C

French to English Medical Medical (general) hepatology
A doctor is being interviewed about recent developments in hepatology. This extract is about hepatitis C complications, which is why I need to be sure what the C stands for here: C-type hepatitis or Child-Pugh class C; in previous cases, when C referred to the Child-Pugh score, this was explicit.

This comes just after a section about screening for hepatocellular carcinoma; it is the interviewer speaking.

"Dans la cirrhose C, alors on va obtenir de plus en plus de réponses virologiques soutenues, faudra-t-il continuer à surveiller ses patients ?"

I hope that context is sufficiently clear: it's difficult for a non-specialist...

BTW, this is a video that I'm subtitling: the more succinct the translation, the better!

Discussion

Victoria Britten (asker) Jul 9, 2015:
@Charles I (of course) made similar checks, with similar results but only found the expression "cirrhose C" as it stands once in the results that came up, and only once in a huge document. In the first page of Google results, the first sub-link to this result - http://sante-medecine.commentcamarche.net/forum/affich-30062... - is headed "Cirrhose stade C". This is why (with all due respect) I posted the question for specialists.
Charles Davis Jul 9, 2015:
@Victoria I've checked out the first dozen or so results for "cirrhose C" that I've found on the Internet ,and in every case it refers to "cirrhose virale C", cirrhosis secondary to Hepatitis C (HVC). As you say in the question, when they mean the stage, some or all of the words "stade", "Child" and "Pugh" always seem to occur. So although there is no certainty, I think it's very likely that the C means Hepatitis C. It certainly appears that "cirrhose C" is quite routinely used in that sense.

Proposed translations

+4
1 hr
Selected

Cirrhosis in Hepatitis C

This is my understanding

CIRRHOSIS IN CHRONIC HEPATITIS C INFECTION
hcvadvocate.org/hcsp/articles/Herrera.html
by JL Herrera - ‎Related articles
CIRRHOSIS IN CHRONIC HEPATITIS C INFECTION. Jorge L. Herrera M.D.. Division of Gastroenterology University of South Alabama College of Medicine

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Note added at 1 hr (2015-07-09 12:27:32 GMT)
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Cirrhosis of the Liver Stages, Causes, Symptoms, Treatments
www.webmd.com/digestive-disorders/cirrhosis-liver
Hepatitis C, fatty liver, and alcohol abuse are the most common causes of cirrhosis of the liver in the U.S., but anything that damages the liver can cause cirrhosis ...

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Note added at 3 hrs (2015-07-09 14:30:43 GMT)
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NO it wouldn't.

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Note added at 7 hrs (2015-07-09 18:30:55 GMT)
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Viekira Pak Regimen Cures 100% of Genotype 1b Hepatitis ...
www.hepctrust.org.uk/.../viekira-pak-regimen-cures-100-geno...
6 days ago - ... which enrolled HCV genotype 1b patients with compensated liver cirrhosis, achieved sustained virological response using AbbVie's Viekira

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Note added at 7 hrs (2015-07-09 18:31:31 GMT)
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How much convincing do you need?

Good luck!
Note from asker:
Hmm, yes, I know hepatitis C is a major cause of cirrhosis, but I'm afraid I remain to be convinced that in this case that is definitely what is being referred to.
So (since this is for subtitles) would "Cirrhosis C" be understandable in English?
Peer comment(s):

agree raptisi
44 mins
Thank you!
agree Charles Davis
49 mins
Thank you!
agree Anne Schulz : Depending on the target audience, "hep C cirrhosis" might work (can't think of anything shorter than that)
3 hrs
Thank you!
agree Gabrielle Leyden
2 days 21 hrs
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thanks very much!"
+1
3 hrs

cirrhosis class C (Child-Pugh classification)

Scores en hépatologie : Child-Pugh, MELD et Maddrey ...
www.revmed.ch/numero-264-page-1803.htm
de L Gex - ‎2010 - ‎Cité 1 fois - ‎Autres articles
Le score de Child-Pugh est un score largement validé et simple d'utilisation. ... et 45-35% chez les patients atteints d'une cirrhose Child-Pugh A, B et C.3,4.
[PDF]

The Child-Pugh score: Prognosis in chronic liver disease ...
www.2minutemedicine.com/the-child-pugh-score-pro...
Traduire cette page
16 juil. 2013 - The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver disease and cirrhosis. ... 29% operative mortality rate, while Class B (n=13) and Class C (n=18) patients had operative ...

I just spoke to a GE specialist and for him it is definitely the Child-Pugh classification that is suggested.

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Note added at 3 heures (2015-07-09 14:18:23 GMT)
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And of course the score applies to other conditions than hepatis C

Laparoscopic Cholecystectomy in Child-Pugh Class C ...
www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC)
Traduire cette page
de G Currò - ‎2005 - ‎Cité 61 fois - ‎Autres articles
Child-Pugh C cirrhotic patients might better benefit from percutaneous drainage ... The cause of cirrhosis was hepatitis B in 9 patients, hepatitis C in 25 patients, .... They did not correlate the outcome by Child-Pugh Score, so it is not possible to ...

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Note added at 3 heures (2015-07-09 14:20:16 GMT)
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I don't know who your subtitles are aimed at but I would use at least "cirrhosis class C" which gets a lo of ghits.

Download pdf - netkey.at
pdf.posterng.netkey.at/download/index.php?...
Traduire cette page
group and liver cirrhosis class C showed an elevation of T2 and T2* values which were statistically significant (T2: 96.8±63.4 vs. 71.7±5,9; T2*: 29.9±5.0 vs.
Note from asker:
Thanks a lot. Do you think that for my subtitles I can get away with "cirrhosis C"?
Peer comment(s):

agree annaAMH : WZW typu C
46 days
Something went wrong...

Reference comments

1 hr
Reference:

Cirrhose C

The context you listed is not really conclusive in terms of "Child-Pugh C cirrhosis" versus "cirrhosis secondary to a C hepatitis".
The following reference uses "cirrhose C" in the latter sense: http://hepatoweb.com/congres/chb2006/Duclos.pdf
Note from asker:
Thanks for your input
Peer comments on this reference comment:

agree Charles Davis
1 hr
Something went wrong...
14 hrs
Reference:

HCV Cirrhosis

http://www.chirurgie-viscerale.org/main/formationcontinue/mi...

"La cirrhose est reconnue comme un état précancéreux du fait des modifications génétiques entrainées par la régénération hépatique constante. Ainsi s'explique la survenue dans une cirrhose de dysplasie hépatocytaire , notamment à grandes cellules dont on sait maintenant qu'elle est associée à un risque majoré de survenue d'un CHC (x2 à 4). Il apparait clairement que la cause de la cirrhose joue un rôle important car certains facteurs étiologiques sont aussi des carcinogènes plus ou moins puissants : ainsi le risque de CHC est évalué

à 20 à 40% dans la cirrhose C, à 15 à 30 % dans la cirrhose B, à 10 à 25% dans la cirrhose hémochromatosique, à 10 à 20% dans la cirrhose alcoolique."
Note from asker:
Thanks for this input
Peer comments on this reference comment:

agree liz askew : Good reference.
8 hrs
Thanks
Something went wrong...
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