Oct 29, 2017 12:33
6 yrs ago
English term
Armenia
Bilingual, PhD
Native in: Armenian (Variant: Eastern) 
, Russian (Variant: Standard-Russia)
Works in: English to Russian, English to Armenian, Armenian to Russian, and 3 more.
mesencephalic cultures
English to Russian
Medical
Medical: Health Care
Epidemiology
Schneider JS, Huang FN, Vemuri MC. 2003. Effects of low-level lead exposure on cell survival and neurite length in primary mesencephalic cultures. Neurotoxicol Teratol 25:555–559.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257652/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257652/
Proposed translations
(Russian)
| 5 | первичная культура мезенцефальных клеток |
Natalie
|
| 3 | см. |
Anna Anatou
|
References
| Абстракт |
Andrey Svitanko
|
Proposed translations
3 hrs
Selected
первичная культура мезенцефальных клеток
primary mesencephalic culture = первичная культура мезенцефальных клеток
Первичная культура - это культура клеток на стадии непосредственно после выделения клеток и до первого посева.
Мезенцефальные клетки - это клетки среднего мозга.
Первичная культура - это культура клеток на стадии непосредственно после выделения клеток и до первого посева.
Мезенцефальные клетки - это клетки среднего мозга.
4 KudoZ points awarded for this answer.
Comment: "Спасибо, Natalie!"
1 hr
Anna Anatou
Türkiye
Türkiye
Native in English
&
Russian
Türkiye
Native in: English , Russian
Works in: English to Russian, Russian to English, English to German
см.
Воздействие слабой свинцовой интоксикации на выживаемость клеток и длину нейрита в первичных мезенцефальных клетках.
/эксперимент на крысах/
/эксперимент на крысах/
Reference comments
46 mins
Andrey Svitanko
Poland
Poland
Native in Russian
Works in field
Poland
RU EN UKR
Native in: Russian 
Works in: English to Russian, Russian to English, Ukrainian to English, and 8 more.
Related KudoZ points
:
76
Reference:
Абстракт
https://www.ncbi.nlm.nih.gov/pubmed/12972068/
Effects of low-level lead exposure on cell survival and neurite length in primary mesencephalic cultures.
Schneider JS1, Huang FN, Vemuri MC.
Author information
Abstract
The effects of low-level lead exposure on survival and neurite length of rat E15 primary ventral mesencephalic dopaminergic neurons were studied. Lead acetate (0.001-10 microM) added to primary cultures for 48 h (in serum-free defined media [DM]) caused a loss of tyrosine hydroxylase (TH)-positive neurons only at the highest concentrations (1 and 10 microM). In contrast, significant effects on neurite length were observed at concentrations as low as 0.001 microM. Lead-induced decrease in neurite length became more apparent at concentrations of 0.01 microM (mean 37.9% decrease) and 0.10 microM lead acetate (mean 43.9% decrease). These data show that very low concentrations of lead, well below the level necessary to adversely affect neuronal survival, can have dramatic effects on neurite growth. These results support recent clinical findings of detrimental effects of low-level lead exposure on brain development.
Effects of low-level lead exposure on cell survival and neurite length in primary mesencephalic cultures.
Schneider JS1, Huang FN, Vemuri MC.
Author information
Abstract
The effects of low-level lead exposure on survival and neurite length of rat E15 primary ventral mesencephalic dopaminergic neurons were studied. Lead acetate (0.001-10 microM) added to primary cultures for 48 h (in serum-free defined media [DM]) caused a loss of tyrosine hydroxylase (TH)-positive neurons only at the highest concentrations (1 and 10 microM). In contrast, significant effects on neurite length were observed at concentrations as low as 0.001 microM. Lead-induced decrease in neurite length became more apparent at concentrations of 0.01 microM (mean 37.9% decrease) and 0.10 microM lead acetate (mean 43.9% decrease). These data show that very low concentrations of lead, well below the level necessary to adversely affect neuronal survival, can have dramatic effects on neurite growth. These results support recent clinical findings of detrimental effects of low-level lead exposure on brain development.
Discussion