Glossary entry (derived from question below)
English term or phrase:
pan-tau
Polish translation:
przeciwciała skierowane przeciwko wszystkim odmianom białka tau
Added to glossary by
Frank Szmulowicz, Ph. D.
Jun 4, 2018 16:29
5 yrs ago
3 viewers *
English term
pan-tau
English to Polish
Medical
Medical (general)
badania kliniczne
Opis badania klinicznego. Pełne zdanie brzmi tak:
"XXX is a pan-tau monoclonal antibody that has potential to treat Alzheimer’s disease."
Przeciwciało monoklonalne to wiadomo, biało tau też wiadomo, ale jak tu przetłumaczyć "pan-tau"? Będe wdzięczny za pomoc.
"XXX is a pan-tau monoclonal antibody that has potential to treat Alzheimer’s disease."
Przeciwciało monoklonalne to wiadomo, biało tau też wiadomo, ale jak tu przetłumaczyć "pan-tau"? Będe wdzięczny za pomoc.
Proposed translations
(Polish)
| 3 +2 | przeciwciała skierowane przeciwko wszystkim odmianom białka tau |
Frank Szmulowicz, Ph. D.
|
Change log
Jun 9, 2018 08:14: Frank Szmulowicz, Ph. D. Created KOG entry
Proposed translations
+2
34 mins
Frank Szmulowicz, Ph. D.
United States
United States
Native in English
&
Polish
Specializes in field
United States
On time, on target, on budget.
Native in: English 
, Polish
Works in: Polish to English, English to Polish, Russian to Polish, and 1 more.
Related KudoZ points
:
2217
Selected
przeciwciała skierowane przeciwko wszystkim odmianom białka tau
Pan means all or every:
The prefix "pan" normally relates to an antibody directed to a type of cell independently from its sub type or localization. Thus, pan endothelial cell marker is an antibody able to recognize all the endothelial cells regardless their subtypes, a pan-cytokeratin marker is directed to all the cytokeratins togheter, a pan-T-cell marker recognizes all the T lymphocytes regardless their types and antigen expression.
https://www.researchgate.net/post/what_does_a_pan_marker_mea...
The prefix "pan" normally relates to an antibody directed to a type of cell independently from its sub type or localization. Thus, pan endothelial cell marker is an antibody able to recognize all the endothelial cells regardless their subtypes, a pan-cytokeratin marker is directed to all the cytokeratins togheter, a pan-T-cell marker recognizes all the T lymphocytes regardless their types and antigen expression.
https://www.researchgate.net/post/what_does_a_pan_marker_mea...
Peer comment(s):
| agree |
Marcin Pustkowski
: Otóż to!
3 mins
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Dziękuję Marcinie. Serdecznie pozdrawiam.
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| agree |
magdadh
1 day 25 mins
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Dziękuję Magdo. Serdecznie pozdrawiam.
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4 KudoZ points awarded for this answer.
Comment: "Dziękuję!"
Reference comments
15 mins
Marcin Pustkowski
Poland
Poland
Native in Polish
Works in field
Poland
Family physician, ATA, tough deadlines
Native in: Polish 
Works in: English to Polish, Polish to English
Related KudoZ points
:
1376
Reference:
In the present study, we have tested the hypothesis that specificity of monoclonal antibodies directed to tau is an important determinant of efficacy in passive immunotherapy. MC1 recognizes an AD-specific tau conformational epitope, while DA31 and PHF1 are high-affinity antibodies detecting pan-tau or p-tau in both normal and Alzheimer’s brain.
Tau Passive Immunotherapy in Mutant P301L... (PDF Download
Tau Passive Immunotherapy in Mutant P301L... (PDF Download
Reference:
Discussion