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Sep 15, 2022 12:14
1 yr ago
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English term

disulfide bond scrambling

English to Serbian Medical Medical: Pharmaceuticals Antibody derivatives
Similarly, Zhang et al. (2010) Anal. Chem. 82: 1090-99 disclose engineering the IgG2 hinge region to limit disulfide bond scrambling and the formation of structural isomers in therapeutic applications.
Proposed translations (Serbian)
3 izmena disulfidnih veza

Proposed translations

56 mins

izmena disulfidnih veza

"However, using of a modification at the limited conditions leads to the formation of intermediate products, in which scrambling of disulfide occurs, which are undesirable in the development of pharmaceutical product."

"Korišćenjem limitiranih uslova modifikacije dolazi do izmene disulfida, koji dovode do stvaranja heterogenih intermedijarnih produkata koji su neželjeni u razvoju farmaceutskog produkta."
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