Oct 27, 2021 00:55
2 yrs ago
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English term
inflammasome
GBK
English to Japanese
Medical
Medical (general)
Definition from
Oxford English Dictionary:
A complex of proteins in the cytoplasm that regulates the activation of enzymes involved in immune and inflammatory responses to pathogens.
Example sentences:
Appropriate inflammasome activation is vital for the host to cope with foreign pathogens or tissue damage, while aberrant inflammasome activation can cause uncontrolled tissue responses that may contribute to various diseases, including autoinflammatory disorders, cardiometabolic diseases, cancer and neurodegenerative diseases. (Nature Portfolio)
The adaptor protein ASC must become linearly ubiquitinated and phosphorylated for inflammasome assembly to occur. After priming, canonical NLRP3 inflammasome activation requires a second, distinct signal to activate NLRP3 and lead to the formation of the NLRP3 inflammasome complex. (National Center for Biotechnology Info)
Potassium ion efflux (a common inflammasome activator) is an essential factor for the assembly and up-regulation of NLRP3 complexes induced by the agonist adenosine triphosphate (ATP). (Molecular Cancer)
Proposed translations
(Japanese)
5 +1 | インフラマソーム | Kayoko Kimura |
Change log
Oct 22, 2021 11:52: changed "Kudoz queue" from "In queue" to "Public"
Oct 27, 2021 00:55: changed "Stage" from "Preparation" to "Submission"
Oct 30, 2021 01:57: changed "Stage" from "Submission" to "Selection"
Nov 6, 2021 01:54:
Nov 26, 2021 01:54:
Dec 26, 2021 01:54:
Proposed translations
+1
8 hrs
インフラマソーム
Definition from
脳科学辞典:
インフラマソームとは、炎症反応を惹起するための細胞内タンパク質複合体である。
Example sentences:
"Danger signals" の番人インフラマソーム (MBL Immunology News)
炎症応答において重要なインフラマソームの構成タンパク質であるASCの活性化の機構 (ライフサイエンス新着論文レ�)
インフラマソームではタンパク分解酵素の一種であるカスパーゼ-1が活性化され、活性型カスパーゼ-1がインターロイキン-1などの炎症性サイトカインの成熟化・分泌を誘導することで炎症が起こります。 (京都大学)
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