Glossary entry (derived from question below)
French term or phrase:
allègement thérapeutique
English translation:
de-escalation of therapy
Added to glossary by
Drmanu49
Jan 13, 2016 06:44
8 yrs ago
10 viewers *
French term
allègement thérapeutique
French to English
Medical
Medical (general)
This term appears in a questionnaire on HIV prevention and treatment, both as a heading and in the following sentence: "L’allègement thérapeutique des ARV (antirétroviraux) consiste à alléger la dose de son traitement, soit en diminuant le nombre de comprimés à prendre à chaque prise, soit en diminuant le nombre de jours par semaine où vous prenez vos médicaments." My searches on the Internet were not fruit. Any help would be much appreciate. TIA
Proposed translations
(English)
| 5 +3 | de-escalation of therapy |
Drmanu49
|
| 3 +2 | regimen simplification |
Charles Davis
|
| 4 | therapeutic relief |
Subodh Jangid
|
Change log
Jan 16, 2016 21:38: Drmanu49 Created KOG entry
Proposed translations
+3
4 hrs
Selected
de-escalation of therapy
This is what we use in our journal.
General Principles of Antimicrobial Therapy
www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC)
Traduire cette page
de S Leekha - 2011 - Cité 95 fois - Autres articles
Important considerations when prescribing antimicrobial therapy include ..... part of the standard combination treatment for HIV infection, is associated with a ..... education, use of clinical order sets and guidelines, de-escalation of therapy, and ...
Principles of Antibiotic Therapy in Severe Infections ...
cid.oxfordjournals.org/content/45/...3/S177.full
Traduire cette page
de S Deresinski - 2007 - Cité 64 fois - Autres articles
Although even appropriate antibiotic therapy drives resistance, inappropriate therapy may also have ... Such de-escalation of therapy, along with the ultimate de-escalation (i.e., discontinuation of therapy as ...... HIV Medicine Association Logo.
Couples of Mixed HIV Status: Clinical Issues and Interventions
https://books.google.fr/books?isbn=1136406727 - Traduire cette page
R Dennis Shelby, Nancy L Beckerman - 2012 - Family & Relationships
... and dependency, 29-30 Aversive behavior shift, couple therapy, 34 Avoidant ... 33, 60 Crisis intervention, 3-4 Crisis resolution, 106-107 De-escalation, EFCT, ...
Clinical Trial Design: Bayesian and Frequentist Adaptive ...
https://books.google.fr/books?isbn=1118183320 - Traduire cette page
Guosheng Yin - 2013 - Medical
... antiviral therapy zidovudine reduces the risk of maternal-to-infant HIV transmission, ... adaptive dose escalation/de-escalation or dose insertion in dose-fin
General Principles of Antimicrobial Therapy
www.ncbi.nlm.nih.gov › ... › PubMed Central (PMC)
Traduire cette page
de S Leekha - 2011 - Cité 95 fois - Autres articles
Important considerations when prescribing antimicrobial therapy include ..... part of the standard combination treatment for HIV infection, is associated with a ..... education, use of clinical order sets and guidelines, de-escalation of therapy, and ...
Principles of Antibiotic Therapy in Severe Infections ...
cid.oxfordjournals.org/content/45/...3/S177.full
Traduire cette page
de S Deresinski - 2007 - Cité 64 fois - Autres articles
Although even appropriate antibiotic therapy drives resistance, inappropriate therapy may also have ... Such de-escalation of therapy, along with the ultimate de-escalation (i.e., discontinuation of therapy as ...... HIV Medicine Association Logo.
Couples of Mixed HIV Status: Clinical Issues and Interventions
https://books.google.fr/books?isbn=1136406727 - Traduire cette page
R Dennis Shelby, Nancy L Beckerman - 2012 - Family & Relationships
... and dependency, 29-30 Aversive behavior shift, couple therapy, 34 Avoidant ... 33, 60 Crisis intervention, 3-4 Crisis resolution, 106-107 De-escalation, EFCT, ...
Clinical Trial Design: Bayesian and Frequentist Adaptive ...
https://books.google.fr/books?isbn=1118183320 - Traduire cette page
Guosheng Yin - 2013 - Medical
... antiviral therapy zidovudine reduces the risk of maternal-to-infant HIV transmission, ... adaptive dose escalation/de-escalation or dose insertion in dose-fin
4 KudoZ points awarded for this answer.
Comment: "Great! Thanks for your help."
10 mins
Subodh Jangid
India
India
India
"The fastest and accurate translation"
Native in: Hindi 
Works in: French to English, English to Hindi, French to Hindi
Related KudoZ points
:
4
therapeutic relief
Used in medical terms.
+2
54 mins
regimen simplification
This is the closest match of expressions in general use, I think. Allègement thérapeutique is an ARV treatment strategy involving a combination of simplification and dosage reduction, once the virus is under control. In English, the terms "deintensification" and "less drug regimen" are occasionally found, but in the context of "regimen simplification".
"Comment un allègement thérapeutique pourrait-il fonctionner concrètement?
Il existe plusieurs propositions:
1. Simplification:
On commence d’abord par instaurer une thérapie antirétrovirale conventionnelle et on la poursuit jusqu’à l’atteinte d’un contrôle virologique. Ensuite, on réduit la pression médicamenteuse en cessant la prise d’un ou plusieurs médicaments, tout en conservant d’autres antirétroviraux. [...]
2. Réduction des doses et/ou de la fréquence de prise:
On débute d’abord une thérapie antirétrovirale aux doses conventionnelles. Une fois que le contrôle virologique est établi, on réduit progressivement les doses ou la fréquence de prise de certains médicaments en s’assurant de maintenir le contrôle du virus."
There's also "congé thérapeutique", but this idea has been abandoned.
http://pvsq.org/2015/02/lallegement-therapeutique-est-ce-pos...
"Regimen Simplification
Synonym(s): Treatment Simplification
Making changes to an HIV treatment regimen to make medication adherence easier. Simplifying an HIV regimen can include reducing the number of antiretroviral (ARV) drugs in the regimen or changing to a combination ARV drug that provides a one-pill, once-daily complete regimen. Other changes can include switching to ARV drugs that cause fewer adverse effects or to ARV drugs that can be taken without food. Benefits of regimen simplification include long-term medication adherence, reduced risk of treatment failure, and improved quality of life."
https://aidsinfo.nih.gov/education-materials/glossary/3287/r...
"Simplification thérapeutiques ou « allègement »" (p. 46)
"Reasons to Consider Treatment Simplification
•Improve adherence, convenience, and quality of life
–Reduce number of doses
–Reduce number of pills
–Reduce number of drugs" (p. 47)
–Reduce costs"
http://www.infectiologie.com/UserFiles/File/medias/enseignem...
"Comment un allègement thérapeutique pourrait-il fonctionner concrètement?
Il existe plusieurs propositions:
1. Simplification:
On commence d’abord par instaurer une thérapie antirétrovirale conventionnelle et on la poursuit jusqu’à l’atteinte d’un contrôle virologique. Ensuite, on réduit la pression médicamenteuse en cessant la prise d’un ou plusieurs médicaments, tout en conservant d’autres antirétroviraux. [...]
2. Réduction des doses et/ou de la fréquence de prise:
On débute d’abord une thérapie antirétrovirale aux doses conventionnelles. Une fois que le contrôle virologique est établi, on réduit progressivement les doses ou la fréquence de prise de certains médicaments en s’assurant de maintenir le contrôle du virus."
There's also "congé thérapeutique", but this idea has been abandoned.
http://pvsq.org/2015/02/lallegement-therapeutique-est-ce-pos...
"Regimen Simplification
Synonym(s): Treatment Simplification
Making changes to an HIV treatment regimen to make medication adherence easier. Simplifying an HIV regimen can include reducing the number of antiretroviral (ARV) drugs in the regimen or changing to a combination ARV drug that provides a one-pill, once-daily complete regimen. Other changes can include switching to ARV drugs that cause fewer adverse effects or to ARV drugs that can be taken without food. Benefits of regimen simplification include long-term medication adherence, reduced risk of treatment failure, and improved quality of life."
https://aidsinfo.nih.gov/education-materials/glossary/3287/r...
"Simplification thérapeutiques ou « allègement »" (p. 46)
"Reasons to Consider Treatment Simplification
•Improve adherence, convenience, and quality of life
–Reduce number of doses
–Reduce number of pills
–Reduce number of drugs" (p. 47)
–Reduce costs"
http://www.infectiologie.com/UserFiles/File/medias/enseignem...
Peer comment(s):
| agree |
Tony M
11 mins
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Thanks, Tony!
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| agree |
Guillaume Brownlie Pacteau
2 hrs
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Merci, Guillaume :)
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| neutral |
Drmanu49
: Simplification does not imply dose reduction as clearly stated in the source text.
3 hrs
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I think you have a point
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| neutral |
philgoddard
: I think that in your reference, "Simplification thérapeutique ou allègement", "ou" must mean "alternatively" rather than "also known as".
9 hrs
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Yes, that could be so.
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